1/ open the app (french translation), go to "Fichier" ("File"), you can find "Configuration" under CTRL+S
2/ now open a tool, ie "Speed up my computer", and immediatly close it
3/ reopen "Fichier", CTRL+S is now "Quitter", that means "Exit"
4/ close Powertools, "Configuration" is back with CTRL+S
Strange thing !!!