Here is another reason why you should be very careful about using the automatic feature of a registry cleaner - like the way you do, Leonardo
After using the Registry cleaner the CPU-use of the process belonging to my soundcard Realtek named "RtkNGUI64.exe" is up to 25%
The reason for this problem is in registry entry related to SRS Labs which apparently supply certain audio enhancement solution to Realtek.
Deleting this registry entry results in massive CPU usage by the RtkNGUI64.exe process. The problem happens even faster if you use registry cleaners because the registry entry is in fact empty and most registry cleaners treat it as useless (empty) and delete it.
Now I have to try to reinstall the missing key again