If there is (or you put) a text file named SuperSoftwareIgnoreList.dat in the Settings subfolder where you have installed RegSupremePro.exe, you can do that.
Just add lines like this to the file:
d:\
G:\
H:\
and so forth
Here's an actual example from my system:
\agere systems pci soft modem
\coupons
\intervideo disclabel
\intervideo windvd creator
\mouse control
\quickload
\realtek high definition audio driver
\targus mouse
a:\
adobe\acrobat
adobe\backup
adobe\mediabrowser
adobe\spelling dictionaries support for reader
adobe\spellingdictionaryfiles
apple\software update
billp studios\detected
d:\
divx\codec
divx\converter
divx\web player
divxnetworks\artwork
divxnetworks\converter
fullcircle\talkback
hp\hp image zone plus
hp\hprbevwr
http://www.adobe.com\adobe® photoshop® album starter edition
imageshack\quickshot
intervideo\disclabel
intervideo\mediacenter
intervideo\wcreator
javasoft\java plug-in
javasoft\java update
javasoft\java web start
k:\
lars hederer\erunt j
lead technologies\dshow
macromedia\flashplayer
microsoft corp\windows media player firefox plugin
mozilla.org\mozilla
mozilla\mozilla
mozillaplugins\@adobe.com/flashplayer
mozillaplugins\@divx.com/divx browser plugin, =
mru-blaster\ignore
mru-blaster\scheduler
pcsi\csi-e
pepimk software\spybotsnd
realtek\aecbf
realtek\alcmonitor
safer networking limited\spybotsnd
sun microsystems\java(tm) 6 update
z:\