Same problem for me. However, stretching did not help.
This problem appears to be totally random - sometimes, when I click on the icon or use the start menu, the main index to the program actually works. More times than not, it is the blank blue screen as shown in this thread.
Also, I cannot close the "blank screen" program without doing a Ctrl - Shift - Esc and then ending the program in the Windows Task Manager. I am using XP Home edition.
Any answers? Any fixes? I have used RegSupreme for almost 5 years now. I want this program but I will not buy it unless/until there is a fix to this problem.