I can confirm the above findings on my AMD system; v.422 Registry Cleaner successfully completes scanning when both "Obsolete software scan" and "Left-over software data scan" modules are not active.
If helpful, here are some system specs (not sure if I've included everything necessary):
- Windows Vista-64 Ultimate
- Asus LiN64-SLI WS mother board
- AMD Athlon 64 FX-74 (3 GHz, quad-core)
- OCZ DDR RAM (6 GB)